Does stopping spironolactone have actually anything to do with gaining weight? If that thought has crossed her mind, you’re not alone. In fact, it is the question of many.

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Like any type of other drug, quitting spironolactone has some impacts on her body. Spironolactone weight acquire after preventing the medicine is one of those effects? Or space those extra pounds after quitting spironolactone simply a coincidence?

Those are the concerns we’ll be answering today.

Table the Content

2 just how Stopping Spironolactone causes Weight Gain4 What room the Other causes of weight Gain?5 methods to mitigate Excess Weight6 FAQ

Spironolactone and also Weight Gain

So, what exactly is the association between spironolactone and also weight gain? Regular management of this drug deserve to sometimes reason weight gain. Again, some have complained of load loss.

Photo by Pavel Danilyuk indigenous PexelsBut it is different if you’re taking spironolactone because that a long time. If you suddenly decide to stop taking this drug, over there is a tiny chance that you will acquire weight. If this happens, then weight obtain occurs really fast in the first few days. 

Yet, it’s ideal not to run to conclusions. Because the reason of weight acquire may it is in unrelated come the medicine as well, the is said that you can stop spironolactone v minimal tap the money symptoms. So, if you have got weight, it’s finest to see your doctor.

How preventing Spironolactone causes Weight Gain

You may think that gaining weight deserve to be the side impact of taking a drug. But, just how does preventing a medication choose spironolactone cause weight gain? there is a facility mechanism behind it. To know that, let’s take a look at the action of the drug.

How Spironolactone acts upon the Body

Spironolactone is a well-known diuretic. It falls under the class ‘potassium-sparing diuretic’. The reason is the it no decrease blood potassium levels.

Other diuretic drugs may severely alleviate potassium. So, drugs prefer spironolactone are beneficial in this aspect.

This drug is provided for the treatment of various conditions. They include:

Aldosteronism Conn’s syndrome Heart failure Nephrotic syndrome HypokalemiaHigh blood pressureEdemaAcne Excessive hair growth

It may seem the the medicine acts almost everywhere the body. Yet that isn’t true. This medicine works only in the kidneys. Her kidneys consist of numerous tiny tube-like structures called nephrons. These nephrons produce urine.

Do friend think spironolactone weight acquire after avoiding it is associated to any kind of kidney issue? just wait because that a little.

Nephrons empty right into larger tubes dubbed collecting tubules and also ducts. Blood ship surround this ducts. And also these vessels deserve to reabsorb the fluid and also ions native the urine within the ducts. But, the reabsorption can’t take place on that is own.

Your adrenal glands develop a hormone referred to as mineralocorticoid or aldosterone. This hormone stimulates the cells of the duct. This reasons reabsorption the water and salts right into the blood from the duct. So, the quantity of liquid increases.

Spironolactone is one aldosterone receptor antagonist. It means that these drug molecules deserve to bind come the receptors shown for aldosterone. So, aldosterone can’t attach to these receptors. Thus, the actions likewise stop.

Hence, fluid and ions no reabsorbed right into the blood. So, the amount of pee increases. Together with that, the amount of liquid in the body additionally decreases.

What Happens once You Suddenly protect against Spironolactone?

On long-term administration of spironolactone, the aldosterone balance shifts. This happens due to the fact that of a an adverse feedback loop. Her body secretes a typical amount the aldosterone.

But because of the drug, aldosterone does no affect. So, much more aldosterone is secreted come compensate. Also then, the human body can’t absorb water.

Thus, if you take it spironolactone for a long time, your aldosterone cheap increases. This outcomes in enhanced blood level of aldosterone.

So, as soon as you suddenly stop taking aldosterone, the receptors space freed. But, the aldosterone level have already been elevated. Thus, this excessive aldosterone causes an ext fluid and ion reabsorption.

Hence your kidneys begin retaining much more fluid the minute you prevent taking spironolactone. This accounts because that the immediate weight get which occurs. The extreme fluid is the reason why you placed on those extra pounds. So, the excessive weight obtain is largely water weight.

You may be wondering how long go rebound water retention lasts. Well, we have good news because that you. The extreme water weight the you gained after preventing spironolactone will certainly go away. Different world have different times of water retention. However, it normally takes just three to six weeks because that the extreme water to go away. 

Your body aldosterone level will reduce overtime after preventing spironolactone. The aldosterone receptors will certainly decrease gradually as well.

When this balance is achieved, your body won’t absorb overfill fluid and also ions. Then, all the extra load you gained because of stopping spironolactone will certainly go away.

Other Side results of Spironolactone

The induced spironolactone weight gain after preventing the medication is a next effect, hardly ever occurs, together I already said. However, that doesn’t occur to everyone. So, if you’re taking spironolactone, girlfriend shouldn’t problem too much.

Quitting will most likely not reason severe load gain. And also even if that does, her weight will be back to typical soon.

Aside indigenous that, over there are other side effects of spironolactone the you must be mindful of. Because that example, avoiding the medicine can an outcome in hypokalemia.

It way too lot potassium deserve to be excreted. This will bring about ionic imbalance and other problems.

However, it is vital to note that spironolactone is a an extremely safe drug. Quitting typically won’t reason adverse effects. However there is a tiny possibility that you’ll experience these. This occur an ext if you’ve been acquisition this medicine for a lengthy time. 

What are the Other causes of load Gain?

You’ve quit spironolactone and also gained part weight. But is that the drug’s fault? We’ve already said the the likelihood of spironolactone withdrawal symptoms is very low. So, if you’ve put on a couple of extra pounds, don’t point your finger in ~ the drug immediately because there may be other causes of load gain. Few of them are: 

1. Sudden adjust in Food Habits:

If you have a suddenly diet change, friend can get weight rapidly. Carbohydrates and also fatty foodstuffs in overabundance can contribute to rapid weight gain. This is usual knowledge.

But, one more cause have the right to be raised salt intake. High salt level in blood retain more fluid. So, too much salty food can be the reason of her weight gain as well.

2. Way of life Changes:

Several lifestyle alters can aspect in weight gain. These include:

not getting enough sleepstressdepressionanxietynot getting sufficient exercisequitting smokingswitching come a sedentary lifestyle.

3. Hormone Imbalance:

Sudden hormone imbalance deserve to lead to quick weight gain. Thyroid hormone and also corticoid hormone imbalance are typical causes. Women v menstrual problems, perimenopause, and also menopausal women have the right to suffer from load gain.

4. Clinical Conditions:

Several diseases and clinical conditions can cause extra weight together well. This include:

Congestive cardiac failureRenal failure and also kidney diseaseLiver cirrhosis and acute liver diseaseCushing’s diseasePolycystic ovarian syndrome

Ways to reduce Excess Weight

Suddenly placing in the extra pounds is a sign of worry. So, it’s herbal that you want to get rid of the excess weight fast. As we’ve discussed above, spironolactone weight get after protecting against the medicine occurs in a very tiny percentage that individuals. So, if you’ve obtained weight, you need to see if there may be any kind of other causes.

But if you’ve kept on your diet and also exercised, and also don’t have any type of other causes, climate spironolactone may be the culprit. In the case, the extra weight is as result of fluid retention. So, it will go away on its own in 3 to 6 weeks.

That being said, you have the right to follow some procedures to mitigate water retention. These can help to lug your spironolactone water retention down. Several of these procedures are: 

1. Tapering off Spironolactone:

 It is never ever a great idea come suddenly stop the medicine. It is especially true if did you do it been acquisition it because that a lengthy time. So, the is best to wean off spironolactone. Friend can try increasing the dosing expression to twin for a week. 

Then, friend can more decrease the dose following week. Or you can increase the moment interval in between doses. Finally, you deserve to stop acquisition the drug altogether.

2. Dietary Measures:

Several dietary measures can help you shed extra weight. These are even an ext effective in the instance of liquid weight. Castle are:

a. Friend can try by to reduce the lot of salt you take it every day. Common salt or sodium chloride has high osmolarity. This causes far-reaching water retention. So, that a good idea to protect against taking extra salt v your food. Girlfriend should try avoiding braided food as well.

b. Eat a well balanced diet deserve to go a long way to to reduce water weight. A well balanced diet with the suitable amount that electrolytes is essential for your body. This restores the electrolyte balance in ~ the body. So, overfill water is no retained.

c. Caffeinated beverages are useful in situation of fluid retention. They have a diuretic effect. It way that they reason the excess fluid to be excreted. So, enjoy it a exorbitant cup the tea or a Starbucks cappuccino will help!

Photo through THE 5th from Pexelsd. There room several foods that are organic diuretics. They include dandelion, ginger, parsley, black cumin, horsetail, parsley, etc. This food item can gain that extra fluid out of your body.

e. You have the right to also shot reducing the carbohydrate and fat intake. Studies have presented that cutting down on polished carbohydrates decreases liquid retention. It can additionally tackle the spironolactone weight acquire after avoiding it.

So, it’s ideal to alleviate sugary food intake. Girlfriend can shot switching to complex carbohydrates for your energy. These incorporate whole-grain wheat, brown rice, brown sugar, etc.

f. Finally, you need to drink the suitable amount the water. Reduce water intake will certainly worsen your liquid retention. Rather, it is best to drink a healthy and balanced amount that water every day. That way, you will minimize the extra fluid retention.

g. Part supplements aid in weight loss as well. Number of supplements are obtainable that can help restore hormone balance and also lose weight.

3. Exercise:

Exercise is the key to every weight loss strategy. Being active and working out has many advantageous effects on your body. This will help in reduce weight, whether it is liquid weight or not.

Exercising helps rise circulation and also improves love function. Also, you’re most likely to lose excessive water with sweating as well. Not just that, exercising avoids fluid buildup in the legs as well.

So, don’t worry if you feel favor you’ve acquired some water weight. An practice regimen will help you get rid of that in no time!

4. Taking treatment of Your psychological Health and Lifestyle:

Your mental health has a direct effect on her body. So it is essential to tend to her mental health and wellness as well.

You should try to manage stress if it’s a part of her life. Gift stressed releases a bunch of chemistry substances the have varied effects. Few of them may even cause water retention. So, being serene can aid in this case.

You need to also shot to obtain the ideal seven to nine hours of sleep. Sleeping is the body’s means of resetting. Insomnia has been linked to the retention of fluid. So, having actually a healthy sleeping habit have the right to make those extra pounds go away.

5. Medication:

You should constantly speak come your physician if you have suddenly acquired weight. They can tell you if that water weight as result of stopping spironolactone or anything else. Lock may also prescribe friend diuretics to help the extreme fluid go away.

There are number of over-the-counter water pills or diuretics. This can aid in this case. However, it is always best to describe your doctor first.


Do you gain weight after preventing spironolactone?

Yes, avoiding spironolactone all of sudden can reason weight gain sometimes.

How to safely prevent taking spironolactone?

You can shot weaning turn off the dose of spironolactone. For example, if you take it it twice a day, try taking it once a week. Then, try taking as soon as every other day because that the next week. Finally, you deserve to stop acquisition the drug altogether.

How lengthy do you should stop taking spironolactone prior to getting pregnant?

You have to stop acquisition spironolactone at least one month prior to getting pregnant.

Why does spironolactone do you get weight?

Spironolactone is a artificial steroid. So, it changes the body’s metabolism and also may reason weight gain.

What room the withdrawal results of spironolactone?

Withdrawal impacts of spironolactone space water retention, weight gain, high blood pressure, resurfacing of acne, etc.


Stopping spironolactone causes sudden weight acquire sometimes. If you’ve rapidly gained some weight, other components may be at play. However, weight gain is possible with long-term spironolactone administration.

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Spironolactone weight acquire after avoiding the medicine is greatly water weight. Thus, you need to take proper steps. Then, in early out time, the an effect will it is in gone.